Cognitive & Nootropic Research Hub
Selank, Semax, Dihexa & Neuroprotective Peptides
A focused research collection on cognitive-enhancing and neuroprotective peptides — covering Selank, Semax, Dihexa, Cerebrolysin, NAP peptide, and BDNF/NGF signaling pathways. Designed for researchers studying neurotrophin modulation, anxiolytic mechanisms, and cognitive function.
Lead Compounds
Selank, Semax, Dihexa
Primary Research Area
Cognitive & Neuroprotection
Key Mechanism
BDNF/NGF upregulation
Research Articles
11+ peer-reviewed overviews
All Cognitive & Nootropic Articles
20 articlesSelank: A Synthetic Heptapeptide Under Investigation for Anxiolytic and Nootropic Properties in Research Models
Selank is a synthetic heptapeptide analogue of tuftsin studied in experimental models for its anxiolytic and nootropic properties, with research focusing on its modulation of GABA, serotonin, and BDNF signaling pathways.
Semax: An ACTH(4-7) Analogue in Neuroprotection and Cognitive Research
Semax is a synthetic heptapeptide analogue of the ACTH(4-7) fragment, developed in Russia and studied for neuroprotective, nootropic, and anxiolytic properties. Research has demonstrated effects on BDNF expression, dopaminergic and serotonergic systems, and cognitive function in animal models and clinical studies.
Selank: Anxiolytic Peptide Research and GABAergic Modulation
A review of Selank's documented anxiolytic properties, GABA-A receptor modulation, and neurotrophic effects in published preclinical and clinical research.
Semax: BDNF Upregulation and Neuroprotection Research
A review of Semax's documented effects on BDNF expression, neuroprotection, and cognitive function in published preclinical and clinical research.
Cognitive Research: Semax + Selank + NAD+ Combination Study
A mechanistic review of the Semax, Selank, and NAD+ combination for cognitive research, examining how the three compounds target complementary aspects of neurological function.
Selank: Anxiolytic Peptide Research and GABAergic Modulation
A review of Selank's pharmacology, including its proposed GABAergic mechanism, BDNF upregulation effects, and the published evidence from Russian clinical trials.
Semax: BDNF Upregulation and Neuroprotection Research
A review of Semax's pharmacology, including its ACTH-derived structure, BDNF upregulation mechanism, and the published evidence for neuroprotective effects in animal models and clinical studies.
Neurotrophin Signaling: How Peptides May Support BDNF and NGF
A review of neurotrophin biology (BDNF, NGF, NT-3) and how research peptides including Semax, Selank, and BPC-157 interact with neurotrophin signaling pathways.
Dihexa: Cognitive Enhancement Research and the HGF/c-Met Pathway
An overview of Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide), a potent hepatocyte growth factor (HGF) modulator studied in experimental models for its effects on synaptic connectivity, memory, and neurological repair.
Selank Deep Dive: Anxiolytic and Nootropic Mechanisms in Research
A deep-dive research overview of Selank, a synthetic analogue of the endogenous peptide tuftsin, examining its anxiolytic, nootropic, and immunomodulatory mechanisms, clinical trials, and comparison with benzodiazepines.
Semax Deep Dive: Cognitive Enhancement and Neuroprotection Research
A deep-dive research overview of Semax, a synthetic ACTH analogue studied for cognitive enhancement, neuroprotection, BDNF upregulation, and stroke recovery, with a review of Russian clinical trials and mechanisms.
Cerebrolysin: Neuroprotection, Neurogenesis & Cognitive Research
A comprehensive review of Cerebrolysin's neurotrophic mechanisms, clinical research in stroke, Alzheimer's disease, and traumatic brain injury, and its role in cognitive enhancement research.
Dihexa: Cognitive Enhancement & Neurogenesis Research Overview
A research overview of Dihexa (PNB-0408), a potent HGF/MET pathway activator studied for its neurogenic and cognitive enhancement effects, including comparisons with BDNF and other nootropic peptides.
Pinealon: Epigenetic Neuroprotection & Pineal Research Overview
A research overview of Pinealon (EDR), a tripeptide developed by the St. Petersburg Institute of Bioregulation, covering its epigenetic mechanisms, neuroprotective effects, and role in pineal gland research.
Selank vs. Semax: Nootropic Peptide Comparison Research
A head-to-head research comparison of Selank and Semax — two Russian-developed nootropic peptides with overlapping but distinct mechanisms, covering anxiety, cognition, BDNF, and clinical research findings.
Selank vs. Traditional Anxiolytics: What Researchers Need to Know
A detailed comparison of Selank's anxiolytic mechanism against classical benzodiazepines and SSRIs, examining preclinical evidence for efficacy, tolerance profile, cognitive effects, and research applications.
Semax Dosing Protocols in Preclinical Models: What the Research Shows
A detailed review of Semax dosing parameters used across preclinical research models, covering route of administration, dose ranges, timing, and endpoint-specific protocol considerations for laboratory researchers.
Semax vs. Selank: Choosing the Right Nootropic Peptide for Your Research Application
A head-to-head comparison of Semax and Selank for laboratory researchers, covering mechanism of action, primary research applications, behavioral endpoints, dosing considerations, and protocol selection guidance.
Where to Buy Semax Research Grade: Quality Standards and Supplier Guide
A sourcing guide for Semax neuropeptide for laboratory research, covering purity verification, COA standards, and supplier evaluation criteria.
Where to Buy Selank Research Grade: Supplier Quality and Verification Guide
A guide for researchers sourcing Selank anxiolytic peptide, covering purity requirements, COA verification, and what to look for in a reliable supplier.
FOR RESEARCH PURPOSES ONLY — All content in this hub is intended strictly for scientific and educational reference. These compounds are not approved for human or animal consumption. Pure Pharm Peptides sells exclusively to qualified researchers.