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Epithalon, GHK-Cu, NAD+, MOTS-c & Longevity Peptides
The most comprehensive research library on anti-aging and longevity peptides — covering Epithalon (telomere extension), GHK-Cu (collagen & skin repair), NAD+ precursors, MOTS-c (mitochondrial function), SS-31, and combination longevity protocols. Designed for researchers studying cellular aging, senescence, and lifespan extension mechanisms.
Lead Compounds
Epithalon, GHK-Cu, NAD+, MOTS-c
Primary Research Area
Cellular Aging & Longevity
Key Mechanism
Telomerase activation & mitochondrial biogenesis
Research Articles
20+ peer-reviewed overviews
GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring human plasma tripeptide with a high affinity for copper ions. Decades of research have implicated it in wound healing, collagen synthesis, anti-inflammatory signaling, and gene expression regulation, making it one of the most studied naturally derived peptides in regenerative medicine research.
NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme present in all living cells, essential for energy metabolism, DNA repair, and sirtuin activation. Research has established that NAD+ levels decline with age, and restoration of NAD+ has been studied as a potential intervention in aging-related metabolic decline.
MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome, making it one of the few known mitochondrial-derived peptides (MDPs). Research has identified roles in metabolic regulation, insulin sensitivity, exercise response, and aging, positioning MOTS-c as a novel intersection between mitochondrial biology and systemic metabolic control.
Glow Blend is a research-grade multi-peptide formulation combining GHK-Cu, Epithalon, and complementary peptides studied for their roles in skin regeneration, collagen synthesis, and cellular anti-aging mechanisms. The combination targets multiple pathways in skin biology simultaneously.
A review of GHK-Cu (copper peptide) and NAD+ as research tools in cellular repair and aging models, examining their distinct mechanisms and the published evidence for each compound.
A review of GHK-Cu's copper-binding chemistry, collagen synthesis stimulation, and antioxidant properties documented in published preclinical and clinical research.
A comparison of NAD+ precursor supplementation (NMN, NR) versus direct NAD+ delivery approaches, examining bioavailability, mechanism differences, and the published evidence base.
A mechanistic analysis of the BPC-157, TB-500, and GHK-Cu combination for tissue repair research, examining how the three compounds target complementary biological pathways.
A mechanistic review of the Epithalon, GHK-Cu, and NAD+ combination for anti-aging research, examining how each compound targets distinct hallmarks of cellular aging.
A mechanistic review of the Semax, Selank, and NAD+ combination for cognitive research, examining how the three compounds target complementary aspects of neurological function.
A comparison of Epithalon and NAD+ as anti-aging research compounds, examining their distinct mechanisms -- telomerase activation vs mitochondrial support -- and the evidence base for each.
A comparison of GHK-Cu and Epidermal Growth Factor (EGF) as skin repair research compounds, examining their distinct mechanisms and the evidence for each in wound healing and skin rejuvenation research.
A comprehensive review of NAD+ biology, the evidence for age-related NAD+ decline, and the published research on NAD+ precursor supplementation in animal models and human clinical trials.
An overview of MOTS-c, a 16-amino acid mitochondrial-derived peptide encoded by the 12S rRNA gene, examining its discovery, mechanism of action in metabolic regulation, exercise mimicry research, and implications for aging biology.
An in-depth look at GHK-Cu (glycyl-L-histidyl-L-lysine copper complex), examining its role in collagen synthesis, wound healing, skin biology, and anti-inflammatory signaling based on published preclinical and clinical research.
A research overview of SS-31 (elamipretide), a mitochondria-targeted tetrapeptide that selectively concentrates in the inner mitochondrial membrane, examining its cardiolipin-stabilizing mechanism and findings in aging, cardiac, and metabolic research models.
An exploration of the research rationale for studying GHK-Cu (copper tripeptide) alongside NAD+ precursors, examining their complementary roles in cellular repair, mitochondrial function, and epigenetic regulation in experimental models.
A research overview examining the complementary mechanisms of Epithalon (Epitalon), a telomerase-activating tetrapeptide, and NAD+ precursors in the context of cellular aging, telomere maintenance, and mitochondrial health research.
Overview of the 2026 peptide research landscape. Examines key longevity compounds -- Epithalon, GHK-Cu, NAD+, BPC-157 -- the biohacking-to-mainstream shift, and the science behind peptide-based longevity research.
An evidence-based review of peptides studied in the context of longevity and anti-aging research, including epitalon, thymosin alpha-1, GHK-Cu, and GLP-1 agonists -- covering the current science, limitations of existing data, and the most promising research directions.
Epitalon and Epithalon are the same tetrapeptide (Ala-Glu-Asp-Gly) — a research overview of telomerase activation, telomere elongation, and longevity studies in model organisms.
A research comparison of NAD+ precursors — NMN, NR, and NAD-linked peptides — covering sirtuin activation, DNA repair, mitochondrial biogenesis, and 2025-2026 clinical trial data.
MOTS-c is a mitochondria-derived peptide encoded in the 12S rRNA gene that regulates metabolic homeostasis, insulin sensitivity, and exercise adaptation — a research overview of its mechanisms and aging studies.
SS-31 (Elamipretide) is a cardiolipin-targeting tetrapeptide that stabilizes the inner mitochondrial membrane, reduces ROS production, and has shown efficacy in heart failure and aging models — a full research overview.
GHK-Cu (copper tripeptide-1) is a naturally occurring plasma peptide that declines with age, stimulating collagen synthesis, wound healing, antioxidant defense, and gene expression remodeling — a complete research overview.
FOR RESEARCH PURPOSES ONLY — All content in this hub is intended strictly for scientific and educational reference. These compounds are not approved for human or animal consumption. Pure Pharm Peptides sells exclusively to qualified researchers.